邱家章教授

来源:动物医学学院 发稿时间:2019-06-24 浏览次数:

姓名:

邱家章

性别:

职称:

教授

硕导/博导:

博导

最高学位:

博士

最高学历:

研究生

办公电话:

邮箱:

qiujz@jlu.edu.cn

详细情况

学科专业:

基础兽医学

研究方向:

重要病原菌致病机制研究新药研发

讲授课程:

博士生:基础兽医学进展

教育经历:

2000.9-2004.7,西南农业大学,大学本科
2004.9-2007.7,西南大学,基础兽医学,硕士学位
2007.9-2012.7,吉林大学,基础兽医学,博士学位

工作经历:

2012.9-2017.2,美国普渡大学   博士后
2017.2-至今,吉林大学动物医学学院 教授

科研项目:

1. 国家自然科学基金面上项目: 嗜肺军团菌OTU家族效应蛋白生化及生物学功能研究(项目编号:317701492018.01-2021.12

学术论文:

1. Qiu J, Sheedlo MJ, Yu K, Tan Y, Nakayasu ES, Das C, Liu X, Luo ZQ. Ubiquitination independent of E1 and E2 enzymes by bacterial effectors. Nature. 2016 May 5;533(7601):120-4.

2. Qiu J, Luo ZQ. Legionella and Coxiella effectors: strength in diversity and activity.  Nat Rev Microbiol. 2017 Jul 17. doi: 10.1038/nrmicro.2017.67. [Epub ahead of print] Review.

3. Qiu J, Yu K, Fei X, Liu Y, Nakayasu ES, Piehowski PD, Shaw JB, Puvar K, Das C, Liu X, Luo ZQ. A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination. Cell Res. 2017 Jul;27(7):865-881.

4. Sheedlo MJ, Qiu J, Tan Y, Paul LN, Luo ZQ, Das C. Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15090-5. (并列第一作者)

5. Hsu F, Luo X, Qiu J, Teng YB, Jin J, Smolka MB, Luo ZQ, Mao Y. The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10538-43. (并列第一作者)

6. Qiu J, Luo ZQ. Effector translocation by the Legionella Dot/Icm type IV secretion system. Curr Top Microbiol Immunol. 2013;376:103-15. (Review)

7. Wang J, Qiu J, Tan W, Zhang Y, Wang H, Zhou X, Liu S, Feng H, Li W, Niu X, Deng X. Fisetin Inhibits Listeria monocytogenes Virulence by Interfering With the Oligomerization of Listeriolysin O. J Infect Dis. 2014 Sep 17. pii: jiu520. [Epub ahead of print]. (并列第一作者)

8. Guo Z, Stephenson R, Qiu J, Zheng S, Luo ZQ. A Legionella effector modulates host cytoskeletal structure by inhibiting actin polymerization. Microbes Infect. 2014 Mar;16(3):225-36.

9. Qiu J, Niu X, Dong J, Wang D, Wang J, Li H, Luo M, Li S, Feng H, Deng X. Baicalin protects mice from Staphylococcus aureus pneumonia via inhibition of the cytolytic activity of α-hemolysin. J Infect Dis. 2012 Jul 15;206(2):292-301.

10. Qiu J, Feng H, Lu J, Xiang H, Wang D, Dong J, Wang J, Wang X, Liu J, Deng X. Eugenol reduces the expression of virulence-related exoproteins in Staphylococcus aureus. Appl Environ Microbiol. 2010 Sep; 76(17):5846-51.