本科生：兽医公共卫生，动物性食品理化检验，免疫学

硕士生：动物性食品卫生与安全前沿/进展，食品病源微生物，动物产品与食品安全检验技术，兽医公共卫生

1994.9-1998.7，吉林农业大学中药材学院经济动物专业攻读学士学位；

2001.9-2004.7，东北林业大学野生动物资源学院动物医学专业攻读硕士学位；

2004.9-2007.6，吉林大学预防兽医学专业攻读博士学位；

2007.7-2009.9，吉林大学人兽共患病研究所讲师；

2009.9-2015.9，吉林大学人兽共患病研究所副教授；

2015.8-2016.8，美国宾夕法尼亚大家访问学者；

2016.8---至今，吉林大学人兽共患病研究所教授。

1.“十四五”国家重点研发计划课题：“口岸冷链运输中典型嗜冷微生物快速检测技术研究与应用”,项目批准号2023YFF0611502，起止时间：2023.11-2026.12，项目经费：110万元，主持人，在研

2.国家质检总署项目，口岸海产食品典型食源性嗜冷菌RPA-Crispr/Cas12a侧流层析试纸研发与应用，项目批准号2023HK126，起止时间：2024.1-2025.12，项目经费：6万元，合作负责人，在研

3.国家自然科学基金面上项目：基于双功能抗原模拟肽偶合物诱导B细胞无能对红肉中Neu5Gc介导的慢性炎症的影响, 项目批准号32072943，2021.01-2024.12，项目经费：58万元，主持，结题

4.吉林省科技发展计划重点研发项目：冷链肉品重要致病性嗜冷菌SHERLOCK检测技术的开发与应用, 项目批准号20210203036SF，2021.07-2024.06，项目经费：30万元，主持，已结题

5.长春市科技局科技发展计划科技攻关项目：红肉新型内源危害因子Neu5Gc快速检测技术开发，项目批准号21ZGN34，2021.11-2023.10，项目经费：50万元，主持，已结题

6.“十三五”国家重点研发计划子课题：牛羊养殖、屠宰和牛奶生产过程中重要食源性病原微生物的流行与传播规律研究，项目批准号2018YFD0500504,2018.06-2021.06，项目经费：45万元，结题

7.“十三五”国家重点研发计划子任务：基于组学的食源性病原微生物快速高通量检测技术—OA检测技术研发，项目批准号2017YFC1601205,2017.06-2021.12，项目经费：26万元，结题

8.横向合作课题：藻类保健品污染毒素快速检测新型抗体开发（2015220101000658），2015.06-2020.6，项目经费：50万元，主持，结题

9.横向合作课题：河豚毒素活性阻断功能抗体开发（2015220101000657），2015.06-2017.12,项目经费：20万元，主持，结题

1.Ruoran Shi^a,1, Hanxiao Li^a,1, Shiying Lu^a,1, Honglin Ren^a,1, Xueyu Hu^a, Jiang Chang^a, Qiang Zhao^a, Yu Zheng^a, Xiaoshi Zhou^b, Lixiong Peng^a, Zengshan Liu^a, Pan Hu^a,⁎CRISPR/Cas13a-based RNA analysis for non-enrichment Listeria monocytogenes in food, Animals and Zoonoses,2024.12. 26 https://doi.org/10.1016/j.azn.2024.12.002i

2.Cong Wang^†, Honglin Ren^†, HanWang, HaosongLi, Jian Guo, Yiran Xiao, Yuxi Guo, Mengdi Liu, Fuchun Duan, Pan Hu, Yansong Li, Zengshan Liu and Shiying Lu^*. The Inhibitory Effect of Early Pregnancy Factor on Red Meat Neu5Gc-Mediated Antibody Production in CMAH^−/−Mice，Nutrients，2024, 16(6), 905, https://doi.org/10.3390/nu16060905, 2024.3.21 online, (2022-2023 IF 5.9，医学大小类2区)

3.Deying Zou^a,b,1, Jiang Chang^a,c,1, Shiying Lu^a,1, Pan Hu^a,1, Kai Zhang^a, Cheng Han^a, Feng Li^a,d, Yansong Li^a, Dan Chi^a, Mengyan Cheng^a, Jianfeng Xu^b, Xiaoli Sun^b, Zengshan Liu^a, Honglin Ren^a,*. Fluorescent dual-signal immunosensor combined with machine learning algorithm for accuracy discrimination of natural Brucella infection and vaccination, Sensors and Actuators: B. Chemical 409 (2024) 135534, https://doi.org/10.1016/j.snb.2024.135534. 2024,2.22 on line (2022-2023 IF 8.4,化学1区TOP)

4.Yuxi Guo †, Honglin Ren †, Han Wang, Yiran Xiao, Cong Wang, Mengdi Liu, Fuchun Duan, Haosong Li, Pan Hu, Yansong Li, Zengshan Liu and Shiying Lu*. Characterization of an Aptamer Targeting Neu5Gc, as an Endogenous Pathogenic Factor Derived from Red Meat. Molecules 2024, 29(6),1273; https://doi.org/10.3390/molecules29061273，2024.3.13 online. (2022-2023 IF 4.6 化学大类2区)

5.Han Wang^#, Yu Zheng^#, Hong-Lin Ren^#, Yi-Ran Xiao, Cong Wang, Jiang Chang, Yu-Xi Guo, Pan Hu, Yan-Song Li, Zeng-Shan Liu, Shi-Ying Lu^*.Alateral flow immunochromatographic strip based on RPA and Quantum dot nanobeads for rapid identification of pathogenic Yersinia enterocolitica. LWT - Food Science and Technology，187 (2023) 115271，https://doi.org/10.1016/j.lwt.2023.115271，2023.9.15 online.（2022-2023 IF 6，农林科学1区，top）

6.Yiran Xiao¹, Honglin Ren¹, Han Wang, Deying Zou, Yixin Liu, Haosong Li, Pan Hu, Yansong Li, Zengshan Liu, Shiying Lu*.A rapid and inexpensive nucleic acid detection platform for Listeria monocytogenes based on the CRISPR/Cas12a system. Talanta,2023 Jul 1:259:124558. doi: 10.1016/j.talanta.2023.124558. Epub 2023 Apr 17. (2022-2023IF 6.1,化学分析化学1区，top)

7.Deying Zou^a,b,1, Jiang Chang^a,1, Shiying Lu^a,1, Jianfeng Xu^b,1, Pan Hu^a, Kai Zhang^a, Xiaoli Sun^b, Wei Guo^b, Yansong Li^a, Zengshan Liu^a, Honglin Ren^a*.Analysis of virulence proteins in pathogenic Acinetobacter baumannii to provide early warning of zoonotic risk. Microbiological Research 266 (2023) 127222，2023，1（2022-2023 IF 6. 7,生物学1区，top）

8.Zhanxu Liu, Nanya Wang, Zhaoli Meng, Shiying Lu*, Gong Peng*. Pseudolaric acid B triggers cell apoptosis by activating AMPK/JNK/DRP1/mitochondrial fission pathway in hepatocellular carcinoma. Toxicology,2023 Jul:493:153556. doi: 10.1016/j.tox.2023.153556. Epub 2023 May 25. (2022-2023IF4.571，医学毒理学2区)

9.Yiran Xiao^#, Honglin Ren^#, Pan Hu, Yang Wang, Han Wang, Yansong Li, Kai Feng, Cong Wang, Qi Cao, Yuxi Guo, Zengshan Liu, Shiying Lu*. Ultra-Sensitive and Rapid Detection of Pathogenic Yersinia enterocolitica Based on the CRISPR/Cas12a Nucleic Acid Identification Platform, Foods, 2022, 11(14): 2160-2160 (2021-2022IF 5.5612，农林科学食品科技2区)

10.Hailing Zhang^1,2, Dongliang Zhang², Han Lu², Deying Zou¹, Bo Hu², Shizhen Lian²and Shiying Lu¹*. Antiviral activity of minkinterferon alpha expressed in the yeast Pichia pastoris. Frontiers in Veterinary Science, 2022,09.14. DOI 10.3389/fvets.2022.976347(2021-2022IF 3.471，农林科学兽医学2区)

11.Xun Guo¹, Jiang Chang¹,Shiying Lu¹,Pan Hu¹,Deying Zou, Yansong Li,Feng Li,Jishan Liu,Qi Cao,Kai Zhang,Junpeng Zhan,Yixin Liu,Xin Yang,Honglin Ren*.Multiantigen epitope fusion recombinant proteins from capsids of serotype 4 fowl adenovirus induce chicken immunity against avian Ankara disease, Veterinary Microbiology, 2023, 278(2023): 109661,2023.3,(2022-2023IF 3.3，农林科学兽医学1区)

12.Han Wang¹, Hong Lin Ren¹, Pan Hu¹, Yan Song Li, Yu Zheng, Qi Cao, Zhan Xu Liu, Zeng Shan Liu, Yong Yang, Shi Ying Lu*. A Fluorescence Immunochromatographic Strip Based on Quantum Dot Nanobeads for the Rapid Detection of Okadaic Acid. Food Analytical Methods. 2022,15 (9), pp.2470-2478 (2021-2022IF 3.498，农林科学大小类3区)

13.Qiang Zhao^#, Pan Hu^#, Qianqian Li, Shasha Zhang, Hanxiao Li, Jiang Chang, Qiujie Jiang, Yu Zheng, Yansong Li, Zengshan Liu, Honglin Ren* & Shiying Lu*. Prevalence and transmission characteristics of Listeria species from ruminants in farm and slaughtering environments in China. Emerging Microbes & Infections, 2021,10:356-364（2020-2021 IF19.568）（小类1区）

14.Yonghong Zha^#, Shiying Lu^#, Pan Hu, Honglin Ren, Zengshan Liu, Weihua Gao, Chengmin Zhao, Yansong Li* and Yu Zhou*. Dual-Modal Immunosensor with Functionalized Gold Nanoparticles for Ultrasensitive Detection of Chloroacetamide Herbicides. ACS Applied Materials & Interfaces, 2021, 13, 6091−6098（2021 IF10.383）

15.Yu Zheng^#, Pan Hu^#, Honglin Ren^#, Han Wang, Qi Cao, Qiang Zhao, Hanxiao Li, Hailing Zhang, Zhanxu Liu, Yansong Li, Cong Wang, Zengshan Liu, Shiying Lu*.RPA-SYBR Green I based instrument-free visual detection for pathogenic Yersinia enterocolitica in meat,Analytical Biochemistry,621(2021):1-6(2021 IF 3.1908)

16.Jiang Chang^#,Xilin Liu^#,Honglin Ren^#,Shiying Lu^#,Meng Li,Song Zhang,Ke Zhao,HanxiaoLi,Xiaoshi Zhou,Lixiong Peng,Zengshan Liu,Pan Hu.Pseudomonas Exotoxin A-Based Immunotherapy Targeting CCK2R-Expressing Colorectal Malignancies: An In Vitro and In Vivo Evaluation, Molecular Pharmaceutics, 2021,18: 2285-2297 (2021 IF 5.364，医学2区)

17.Han Wang^a1, Zong-Cheng Wu^ab1, Pan Hu^a1, Hong-Lin Ren^a1, Yan-Song Li^a, Yu Zheng^a, Cong Wang^a, Zeng-Shan Liu^a, Shi-Ying Lu^a*. Identification of chicken-derived scFv against N-glycolylneuraminic acid retrieved from an immune library by phage display. Protein Expression and Purification, Volume 182, June 2021, 105841（2021 IF2.0248）

18.Hong Zhang^#, Shi-Ying Lu^#, Honglin Ren, Ke Zhao, Yansong Li, Yuting Guan, Hanxiao Li, Pan Hu* and Zengshan Liu*. Cytotoxicity and degradation product identification of thermally treated ceftiofur, RSC Adv., 2020, 10, 18407–18417（2019 IF 3.119）

19.Hong Zhang^#, Shi-Ying Lu^#, Honglin Ren, Ke Zhao, Yansong Li, Yuting Guan, Hanxiao Li, Pan Hu* and Zengshan Liu*. Acute oral toxicity and acute intraperitoneal studies of thermally treated ceftiofur[J]. Chemical and Pharmaceutical Bulletin, 2020,68,1061-1068.（2019 IF 1.416）

20.Shi-Jun Zhang^#, Lu-Lu Wang^#, Shi-Ying Lu^#, Pan Hu, Yan-Song Li, Ying Zhang, Heng-Zhen Chang, Fei-Fei Zhai, Zeng-Shan Liu, Zhao-Hui Li, Hong-Lin Ren*. A novel, rapid, and simple PMA-qPCR method for detection and counting of viable Brucella organisms，J Vet Res 64, 253-261, 2020（2019 IF 1.039）

21.Shi-Jun Zhang^1#, Xing Guo^12#, Pan Hu^1#, Shi-Ying Lu^1#, Nan-Nan Liu¹,Bao-Quan Fu³, Nan Wang⁴, Yan-Song Li¹, Lu-Lu Wang¹, Jiang Chang¹,Heng-Zhen Chang¹, Zeng-Shan Liu¹, Yu Zhou¹, and Hong-Lin Ren^1*.Characterization of a Novel Interleukin-1 Receptor Antagonist from Sheep (Ovis aries). JOURNAL OF INTERFERON & CYTOKINE RESEARCH,40（5）:268-278,2020（2019 IF 2.032）

22.Lu-Lu Wang^1†, Xiao-Feng Chen^1†, Pan Hu^1†, Shi-Ying Lu^1†, Bao-Quan Fu², Yan-Song Li¹, Fei-Fei Zhai¹, Dan-Di Ju¹, Shi-Jun Zhang¹, Yi-Ming Shui¹, Jiang Chang¹, Xiao-Long Ma^1,3, Bing Su¹, Yu Zhou^1,Zeng-Shan Liu¹and Hong-Lin Ren^1*. Host Prdx6 contributing to the intracellular survival of Brucella suis S2 strain, BMC Veterinary Research (2019) 15:304

23.Lu-Lu Wang^1#, Shi-Ying Lu^1#, Pan Hu¹,Bao-Quan Fu², Yan-Song Li¹, Fei-Fei Zhai¹, Dan-Di Ju¹,Shi-Jun Zhang¹, Bing Su¹, Yu Zhou¹, Zeng-Shan Liu¹, Hong-Lin Ren¹.Construction and activity analyses of single functional mouse peroxiredoxin 6 (Prdx6), J Vet Res 63, 99-105, 2019（2018 IF 1.039）

24.Sheng Gong^1#, Honglin Ren^1#, Chao Lin, Pan Hu, Ruiyun Tian, Zengshan Liu, Yansong Li, Yu Zhou,Yong Yang, Shiying Lu^∗. Immunochromatographic strip biosensor for the rapid detection of N-glycolylneuraminic acid based on aptamer-conjugated nanoparticle. Analytical Biochemistry. 561–562 (2018) 52–58（2017 IF 2.275）

25.Yi-Ming Shui^a,1#, Shi-Ying Lu^a,1#, Xing Guo^a,c, Xi-Lin Liu^a, Bao-Quan Fu^b, Pan Hu^a, Lin-Lin Qu^a, Nan-Nan Liu^a, Yan-Song Li^a, Lu-Lu Wang^a, Fei-Fei Zhai^a, Dan-Di Ju^a, Zeng-Shan Liu^a, Yu Zhou^a,Hong-Lin Ren^a,∗Molecular characterization and differential expression analysis of interleukin 1β from Ovis aries, Microbial Pathogenesis , 2018,116: 180-188

26.Yong-Jie Yang^1,2#, Zeng-Shan Liu¹, Shi-Ying Lu^1#, Pan Hu¹, Chuang Li², Waqas Ahmad^1,5, Yan-Song Li¹, Yun-Ming Xu^1,3, Feng Tang^1,4, Yu Zhou¹, Hong-Lin Ren^1*,Cloning and differential expression analyses of Cdc42 from sheep,J Vet Res,2018,62, 113-119

27.Pan Hu,†, Song Zhang,†,Shi-ying Lu†, Meng Li, Jiang Chang, Meng-yun Wang, Chang Li, Ke Zhao,Yu-Ting Guan,Yuan-Yuan Zhang, Yan-Song Li, Yu Zhou, Zeng-Shan Liu*, Ou Bai*and Hong-Lin Ren*.An efficient scheme for purification of a novel recombinant immunotoxin, rCCK8PE38, for anti-tumour experiments,Biomedical Chromatography: BMC,2018,32(6): e4197. (2017 IF 1.613)

1.并列主编《人兽共患病》,北京,科学出版社,2014年11月出版

2.副主编《动物检疫检验学》,北京,科学出版社,2012年9月出版

3.参编《兽医公共卫生学》,北京,中国轻工业出版社,2009年11月出版，2016年再版

4.参编《当代世界人兽共患病学》,四川出版集团,四川科技出版社,2011年3月出版

5.参编《食品安全学》,北京,中国轻工业出版社,2013年4月出版

6.参编《生物毒素学》,北京,科学出版社,2021年6月出版

1.卢士英，李焓笑，柳溪林，胡盼，任洪林，柳增善，李岩松，赵强，郑宇，常江.一种基于SHERLOCK检测单增李斯特菌的现场可视化试剂盒及应用,国家发明专利，授权专利号ZL 2020 1 0846569.5，授权公告号：CN 114075607 B，授权日2024.2.20

2.卢士英，王菡，王洋，李岩松，任洪林，胡盼，柳增善，杨勇，周 玉，曹旗，郑宇.一种腹泻性贝毒大田软海绵酸荧光检测试纸及其检测方法，国家发明专利,申请号: 201910330343.7，授权号：ZL 2019 1 0330343.7,授权公告号：CN 110018145 B，授权日2022.01.25

3.卢士英,张虹,柳增善,胡盼,任洪林,李岩松,周玉,赵 柯,王菡,一种头孢噻呋降解产物的制备方法,国家发明专利,申请号: 201910904943.X, 专利号：ZL 2019 1 0904943.X，授权公告号：CN 110590698 B，授权日2021.11.16

4.卢士英,任洪林,李岩松,柳增善,周 玉,孟宪梅,李兆辉,于师宇,林 超,闫东明,王里奇,李 乐.一种海洋贝毒素单抗制备方法, 授权时间：2016.08.03，国家发明专利,中国，授权专利号:ZL201010153343.3

5.卢士英,柳增善,任洪林,李岩松,周玉,刘东,宋杰,张茂林,李兆辉.一种梅花鹿朊蛋白免疫学检测方法, 国家发明专利,中国, 授权时间：2014.08.06，授权专利号:ZL201210009078.0

6.卢士英,李岩松,柳增善,任洪林,周玉,冯小丽,宋杰,张茂林,李兆辉.一种卵白蛋白双抗夹心ELISA检测方法, 授权日：2013.12，国家发明专利，中国,授权专利号:ZL201210010496.1

7.卢士英，郑宇，柳溪林，任洪林，胡盼，柳增善，李岩松，赵强，王菡，肖毅然，王聪，鉴定致病性小肠结肠炎耶尔森氏菌的特异性引物对、检测试剂盒及其应用, 中国发明专利,申请爱理号,202110397506.0，申请日2021.04.14

8.卢士英，肖毅然，柳溪林，任洪林，胡盼，李岩松，王洋，王菡，王聪，郭禹汐.一种致病性小肠结肠炎耶尔森氏菌检测用引物对和CRISPR/Cas12a检测试剂盒, 中国发明专利,申请受理号,CN202210607278.X.申请日2022.05.31

9.卢士英，肖毅然，任洪林，李香荷，王菡，胡盼，李岩松，柳增善，王聪，郭禹汐.一种基于CRISPR/Cas12a检测单增李斯特菌的现场可视化试剂盒及应用，中国发明专利,申请受理号,202211090936.9,申请日2022.09.08，

10.卢士英,郭禹汐,王菡,任洪林,胡盼,李岩松,王洋,柳溪林,张博,李浩菘. 一种检测 Neu5Gc 的适配体和基于 AP-Cas12a 检测 Neu5Gc 的方法,中国发明专利,申请受理号,2024103956307,申请日2024.04.02

11.卢士英，王菡，刘蒙迪，李岩松，柳溪林，王洋，任洪林，胡盼，卢强，段芙春.一种同时模拟游离和结合态Neu5Gc的适配体、试剂盒及其应用. 中国发明专利,申请受理号,2024118865033,申请日2024.12.20

1.参编《人兽共患病学（第二版）》,北京,科学出版社,2024年6月出版

2.并列主编《人兽共患病学》,北京,科学出版社,2014年11月出版

3.副主编《动物检疫检验学》,北京,科学出版社,2012年9月出版

4.参编《兽医公共卫生学》,北京,中国轻工业出版社,2009年11月出版，2016年再版

5.参编《当代世界人兽共患病学》,四川出版集团,四川科技出版社,2011年3月出版

6.参编《食品安全学》,北京,中国轻工业出版社,2013年4月出版

7.参编《生物毒素学》,北京,科学出版社,2021年6月出版

8.参编《人兽共患病》第二版,北京,科学出版社,2024年6月出版

1.张海玲，王建科，廉士珍，张蕾，卢士英，孟庆峰，王伟利，闫喜军.水貂病毒性肠炎诊断及防治技术研究与应用，吉林省科学技术进步奖，三等，证书编号:2024J30068,2024.11.12

2.柳增善,任洪林,卢士英,周玉,孟宪梅,李岩松,李兆辉,于师宇,张俊辉,李研东,任立松,王颖,饶星.“食品污染物免疫学快速检测技术基础研究”吉林省科技进步二等奖，证书编号2010J20029,2010,12

3.周玉,李岩松,孟星宇,张娞媛,卢士英,胡盼,任洪林,张俊辉,杨丽，柳增善,全国商业科技进步奖,一等奖，食品和水安全纳米生物探针的设计合成及快检体系构建,中国商业联合会,2017-1-25-R05,2017.12

4.于光,柳增善,卢士英,周 玉,李岩松,任洪林,张代辉,霍方珍.“大田软海绵酸免疫学检测技术研究”,吉林省出入境检验检疫局科技兴检三等奖.证书编号：2007-JL38-RO,2007

国家自然科学基委通讯评审专家，吉林省人兽共患病学会理事，中国畜牧兽医学会兽医食品卫生分会常务理事。