LI Zi

  Title：Associate Professor

  Email：lizi1227@jlu.edu.cn

Li Zi obtained her B.Agr. from Jilin University in 2013. She then went to College of Animal Medicine and did her Ph.D. in “veterinary molecular pathology and immunopathology”. In 2018, as a postdoctoral fellow, she had worked with Prof. Wang Dacheng in “zoology” in College of Animal Science in Jilin University for two years. In 2020, as a lecturer, she joined Prof. GAO Feng group at Jilin University and did research on pathogenic mechanism, differential diagnosis and vaccine development of animal viral infectious diseases. 

Research Interests：

·Coronavirus infectious disease

·Molecular pathology and immunopathology

·Neurodegeneration

·Pathogenic mechanism

·Vaccine development

Selected Publications：

1. Lv X^#, Li Z^#, Guan J, Hu S, Zhang J, Lan Y, Zhao K, Lu H, Song D, He H, Gao F, He W^*. Porcine Hemagglutinating Encephalomyelitis Virus Activation of the Integrin α5β1-FAK-Cofilin Pathway Causes Cytoskeletal Rearrangement To Promote Its Invasion of N2a Cells. J Virol. 2019 Feb 19;93(5).

2. Li Z^#, Zhao K^#, Lv X, Lan Y, Hu S, Shi J, Guan J, Yang Y, Lu H, He H, Gao F, He W^*. Ulk1 Governs Nerve Growth Factor/TrkA Signaling by Mediating Rab5 GTPase Activation in Porcine Hemagglutinating Encephalomyelitis Virus-Induced Neurodegenerative Disorders. J Virol. 2018 Jul 31;92(16).

3. Li Z^#, Zhao K^#, Lv X, Lan Y, Hu S, Shi J, Guan J, Yang Y, Lu H, He H, Gao F, He W*. Porcine Hemagglutinating Encephalomyelitis Virus Enters Neuro-2a Cells via Clathrin-Mediated Endocytosis in a Rab5-, Cholesterol-, and pH-Dependent Manner. J Virol. 2017 Nov 14; 91(23): e01083-17.

4. Lv X^#, Li Z^#, Guan J, Zhang J, Xu B, He W, Lan Y, Zhao K, Lu H, Song D, Gao F*. ATN-161 reduces virus proliferation in PHEV-infected mice by inhibiting the integrin α5β1-FAK signaling pathway. Vet Microbiol. 2019 Jun;233:147-153.

5. Hu S^#, Li Z^#, Lan Y, Guan J, Zhao K, Chu D, Fan G, Guo Y, Gao F, He W*. MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication. Front Microbiol. 2020 Feb 20;11:105.