HAN Wenyu

Title： Professor

Specialties：Bacterial resistance and new biological antibacterial  agent

Email：hanwy@jlu.edu.cn

Research Interests：                        

· The mechanism of Bacterial resistance and its elimination.

· Discovery of new antimicrobial peptide resources, the Antibacterial mechanism, and its Industrialization.

· The phages of important antibacterial-resistant bacteria.

· The mechanism of antibacterial protein derived from phages.

Research Project:

1. National Natural Science Foundation of China, major project (U19A2038), 2020/01-2023/12.

2. National Natural Science Foundation of China, major project (31130072), 2012/01-2016/12.

3. National Natural Science Foundation of China, general Project (31572553), 2016/01-2019/12.

4. National Key R&D Program (2017YFD0501000), Sub-topics, 2017/017-2020/12.

Selected Publications：

1. Xue Y^#, …, Han W^* and Gu J^*. The Yersinia Phage X1 Administered Orally Efficiently Protects a Murine Chronic Enteritis Model Against Yersinia enterocolitica Infection. Front. Microbiol. 2020. 11:351.

2. Ji Y^#, …, Han W^*, Gu J^*. Preventive effect of the phage VB-SavM-JYL01 on rabbit necrotizing pneumonia caused by Staphylococcus aureus. Vet Microbiol. 2019 Feb;229:72-80.

3. Zhang Y^#, …, Han W^*, Gu J^*. Antibacterial effects of phage lysin LysGH15 on planktonic cells and biofilms of diverse staphylococci. Appl Environ Microbiol. 2018 Jul 17;84(15).

4. Gu J, …, Han W^*. Therapeutic effect of Pseudomonas aeruginosa phage YH30 on mink hemorrhagic pneumonia. Vet Microbiol. 2016 Jul 15;190:5-11.

5. Gu J, …, Han W^*. Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin. PLoS Pathog. 2014 May 15;10(5):e1004109.

Awards and academic：

1. The first prize of Jilin Province Science and Technology Progress Award (2012).

2. The first prize of Jilin Province Science and Technology Progress Award (2009).

3. Famous Teacher of Jilin Province.

4. Member of the State Council Veterinary Discipline Evaluation Group.

5. Deputy Chairman of the Animal Medicine Teaching Steering Committee of the Ministry of Education.

6. The reviewer of Appl Environ Microbiol, Frontier in microbiology, Antibiotics, etc..