本科生：动物生理学、动物机能学实验技术、神经生物学

硕士生：动物机能学实验技术、动物生理学前沿

1. 2017年1月~至今，吉林大学，动物医学学院，教授

2. 2013年1月~2016年12月，吉林大学，动物医学学院，教授，副院长

3. 2006年9~2013年1月，吉林大学，畜牧兽医学院，教授

4. 2004年9~2006年8月，吉林大学，畜牧兽医学院，副教授

5. 2001年9~2004年8月，解放军军需大学，动物生理学教研室，副教授

6. 1990年9~2001年8月，解放军农牧大学，动物生理学教研室，讲师

7. 1984年8~1990年8月，解放军兽医大学，动物生理学教研室，助教

1.疑核对大鼠炎症性肠病相关细胞因子的调控机制，国家自然科学基金项目，项目编号：30671535，2007年1月~2009年12月，30万，主持。

2. IL-21在大鼠炎症性肠病中的作用及其中枢机制，国家自然科学基金项目，项目编号：30871840，2009年1月~2011年12月，40万，主持。

3. NPY在大鼠炎症性肠病中的作用及其机制，国家自然科学基金，项目编号：31072100，2011年1月~2013年12月，40万，主持。

4.乳脂肪和乳蛋白合成关键物质代谢的神经内分泌调节机制，国家重点基础研究发展计划（973计划子课题），项目编号：2011CB100805，2011年1月~2015年8月，30万，主持。

5.牛奶重要营养品质改良关键技术的研究与示范，吉林省重点科技攻关项目，项目编号：20130206036N Y，2013年1月~2015年12月，13万，主持。

6. Ghrelin对奶牛乳蛋白合成的影响及机制研究，国家自然科学基金，项目编号：31372396，2014年1月~2017年12月，85万，主持。

7. KISS-1/GPR54系统对奶牛乳腺上皮细胞合成乳蛋白的影响及其机制，国家自然基金，项目编号：31672509，2017年1月~2020年12月，62万，主持。

8.畜禽应激综合症防控技术研究，“十三五”国家重点研发计划，项目编号：2016YFD0501210，2016年7月~2020年12月，67.5万，子课题主持。

9. GPR109A调控奶牛乳腺乳蛋白合成的机理研究，国家自然科学基金，项目编号：31873004，2019年1月~2022年12月，59万，主持。

10. MAMs调控线粒体质量控制在乳腺氧化应激中的作用及其机制，国家自然科学基金，项目编号：32172807，2022年1月~2025年12月，58万，主持。

1. Kai Wang, Chuanping Yuan, Wei Wang, Zhanqing Yang, Wei Cui, Lianzhi Mu, Zhanpeng Yue, Xiuling Yin, Zhongming Hu, Juxiong Liu*, Expression of interleukin 6 in brain and colon of rats with TNBS-induced colitis, World journal of gastroenterology, 2010. 5. 14, 16(8): 2252-2259.

2. Zuhua Yu#, Man Teng#, Jun Luo*, Xinwei Wang, Ke Ding, Lele Yu, Jingwei Su, Jiaqi Chi, Pu Zhao, Bo Hu, Gaiping Zhang, Juxiong Liu*, Molecular characteristics and evolutionary analysis of field Marek’s disease virus prevalent in vaccinated chicken flocks in recent years in China, Virus genes, 2013. 10, 47(2): 282-291.

3. Jianfa Wang#, Shoupeng Fu#, Sunan Li#, Zhongming Hu#, Wenjing Xue, Zhiqiang Li, Bingxu Huang, Qingkang Lv, Juxiong Liu*, Wei Wang*, Short-chain fatty acids inhibit growth hormone and prolactin gene transcription via cAMP/PKA/CREB signaling pathway in dairy cow anterior pituitary cells, International journal of molecular sciences, 2013. 10. 30, 14(11): 21474-21488. 5-Year IF=4.331

4. Sunan Li#, Wang Wei#, Shoupeng Fu#, Jianfa Wang#, Hongmei Liu, Shanshan Xie, Bingrun Liu, Yang Li, Qingkang Lv, Zhiqiang Li, Wenjing Xue, Bingxu Huang, Wei Chen*, Juxiong Liu*, IL-21 Modulates Release of Proinflammatory Cytokines in LPS-Stimulated Macrophages through Distinct Signaling Pathways, Mediators of inflammation. 2013; 2013. 12. 26, 2013: 548073.

5. Shoupeng Fu#, Sunan Li#, Jianfa Wang#, Yang Li#, Shanshan Xie, Wenjing Xue, Hongmei Liu, Bingxu Huang, Qingkang Lv, Liancheng Lei, Guowen Liu, Wei Wang*, Juxiong Liu*, BHBA suppresses LPS-induced inflammation in BV-2 cells by inhibiting NF-κB activation, Mediators of inflammation, 2014. 4. 6, 2014: 983401.

6. Shoupeng Fu#, Wei Wang#, Bingrun Liu#, Huanmin Yang#, Hong Ji#, Zhanqing Yang, Bin Guo, Juxiong Liu*, Jianfa Wang*, β-hydroxybutyric sodium salt inhibition of growth hormone and prolactin secretion via the cAMP/PKA/CREB and AMPK signaling pathways in dairy cow anterior pituitary cells, International journal of molecular sciences, 2015. 2. 16, 16(2): 4265-4280.

7. Shoupeng Fu#, Jianfa Wang#, Wenjing Xue#, Hongmei Liu#, Bingrun Liu#, Yalong Zeng, Sunan Li, Bingxu Huang, Qingkang Lv, Wei Wang*, Juxiong Liu*, Anti-inflammatory effects of BHBA in both in vivo and in vitro parkinson’s disease models are mediated by GPR109A dependent mechanisms. Journal of neuroinflammation, 2015. 1. 17,12: 9.

8. Shoupeng Fu#, Bingrun Liu#, Jianfa Wang#, Wenjing Xue#, Hongmei Liu, Yalong Zeng, Bingxu Huang, Sunan Li, Qingkang Lv, Wei Wang*, Juxiong Liu*, β-hydroxybutyric acid inhibits growth hormone-releasing hormone synthesis and secretion through the GPR109A/ERK1/2 signaling pathway in the hypothalamus, Journal of neuroendocrinology, 2015. 3, 27(3): 212-222.

9. Guangxin Chen#, Shoupeng Fu#, Wenqian Feng, Bingxu Huang, Shiyao Xu, Wei Wang*, Juxiong Liu*, AMP010014A09 in Sus Scrofa encodes an analog of G protein-coupled receptor 109a, which mediates the anti-inflammatory effects of beta-hydroxybutyric acid, Cellular physiology and biochemistry, 2017. 7. 17, 42(4): 1420-1430.

10. Bingxu Huang#, Dewei He#, Guangxin Chen, Xin Ran, Wenjin Guo, Xingchi Kan, Wei Wang, Dianfeng Liu, Shoupeng Fu*, Juxiong Liu*, α-Cyperone inhibits LPS-induced inflammation in BV-2 cells through activation of Akt/Nrf2/HO-1 and suppression of the NF-κB pathway, Food & Function, 2018. 5. 23, 9(5): 2735-2743.

11. Guangxin Chen#, Xin Ran#, Bai Li#, Yuhang Li, Dewei He, Bingxu Huang, Shoupeng Fu, Juxiong Liu*, Wei Wang*, Sodium butyrate inhibits inflammation and maintains epithelium barrier integrity in a TNBS-induced inflammatory bowel disease mice model, Ebiomedicine, 2018. 4, 30(2018): 317-325.

12. Wenqian Feng#, Yancheng Wu#, Guangxin Chen#, Shoupeng Fu#, Bai Li, Bingxu Huang, Dali Wang, Wei Wang*, Juxiong Liu*, Sodium butyrate attenuates diarrhea in weaned piglets and promotes tight junction protein expression in colon in a GPR109A-dependent manner, Cellular physiology and biochemistry, 2018. 6. 27, 47(4):1617-1629.

13. Yanwei Li#, Qian Gong#, Wenjin Guo, Xingchi Kan, Dianwen Xu, He Ma, Shoupeng Fu*, Juxiong Liu*, Farrerol relieve Lipopolysaccharide (LPS)-induced mastitis by inhibiting AKT/NF-κB p65, ERK1/2 and P38 signaling pathway, International journal of molecular sciences, 2018. 6. 14, 19(6).

14. Qian Gong#, Yanwei Li#, He Ma, Wenjin Guo, Xingchi Kan, Dianwen Xu, Juxiong Liu*, Shoupeng Fu*, Peiminine protects against lipopolysaccharide-induced mastitis by inhibiting the AKT/NF-κB, ERK1/2 and p38 signaling pathways, International journal of molecular sciences, 2018. 9. 6, 19(9): 2637.

15. Guangxin Chen#, Bingxu Huang#, Shoupeng Fu#, Bai Li, Xin Ran, Dewei He, Liqiang Jiang, Yuhang Li, Bingdong Liu, Liwei Xie*, Juxiong Liu*, Wei Wang*, G protein-coupled receptor 109A and host microbiota modulate intestinal epithelial integrity during sepsis, Frontiers in immunology, 2018. 9. 13, 9: 2079.

16. Wenjin Guo#, Bingrun Liu#, Guiqiu Hu#, Xingchi Kan, Yanwei Li, Qian Gong, Dianwen Xu, He Ma, Yu Cao, Bingxu Huang, Shoupeng Fu*, Juxiong Liu*, Vanillin protects the blood-milk barrier and inhibits the inflammatory response in LPS-induced mastitis in mice, Toxicology and applied pharmacology, 2019. 2. 15, 365(2019): 9-18.

17. Xingchi Kan#, Bingrun Liu#, Wenjin Guo#, Libin Wei, Yuanqing Lin, Yingcheng Guo, Qian Gong, Yanwei Li, Dianwen Xu, Yu Cao, Bingxu Huang, Aiwen Dong, He Ma, Shoupeng Fu*, Juxiong Liu*, Myricetin relieves LPS‐induced mastitis by inhibiting inflammatory response and repairing the blood-milk barrier, Journal of cellular physiology, 2019. 2. 11, 234(9): 16252-16262.

18. Wenjin Guo#, Bingrun Liu#, Yunhou Yin#, Xingchi Kan, Qian Gong, Yanwei Li, Yu Cao, Jianfa Wang, Dianwen Xu, He Ma, Shoupeng Fu*, Juxiong Liu*, Licochalcone A Protects the Blood-Milk Barrier Integrity and Relieves the Inflammatory Response in LPS-Induced Mastitis, Frontiers in immunology, 2019. 2. 25, 10: 287.

19. Dianwen Xu#, Juxiong Liu#, He Ma, Wenjin Guo, Jiaxin Wang, Xingchi Kan, Yanwei Li, Qian Gong, Yu Cao, Ji Cheng, Shoupeng Fu*, Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy, International immunopharmacology, 2020.1. 78(2020).

20. Wenjin Guo#, Juxiong Liu#, Jingxuan Sun, Qian Gong, He Ma, Xingchi Kan, Yu Cao, Jianfa Wang, Shoupeng Fu*, Butyrate alleviates oxidative stress by regulating NRF2 nuclear accumulation and H3K9/14 acetylation via GPR109A in bovine mammary epithelial cells and mammary glands, Free radical biology and medicine, 2020. 5. 20, 152(2020): 728-742.

21. Wenjin Guo#, Juxiong Liu#, Wen Li, He Ma, Qian Gong, Xingchi Kan, Yu Cao, Jianfa Wang, Shoupeng Fu*, Niacin alleviates dairy cow mastitis by regulating the GPR109A/AMPK/NRF2 signaling pathway, International journal of molecular sciences, 2020. 5. 8. 21(9): 3321.

22. Yanwei Li#, Yu Cao#, Jiaxin Wang#, Shoupeng Fu#, Ji Cheng, Lijun Ma, Qing Zhang, Wenjin Guo, Xingchi Kan, Juxiong Liu*. Kp-10 promotes bovine mammary epithelial cell proliferation by activating GPR54 and its downstream signaling pathways, Journal of cellular physiology, 2020. 5, 235(5): 4481-4493.

23. Wenjin Guo#, Juxiong Liu#, Yufei Zhang, He Ma, Yuhang Li, Qian Gong, Yu Cao, Guiqiu Hu, Shengnan Xie, Shoupeng Fu*, Dehydroandrographolide inhibits mastitis by activating autophagy without affecting intestinal flora, Aging-US, 2020. 7. 23, 12(14): 14050-14065.

24. Xingchi Kan#, Juxiong Liu#, Yingsheng Chen, Wenjin Guo, Dianwen Xu, Ji Cheng, Yu Cao, Zhanqing Yang, Shoupeng Fu*, Myricetin protects against H2O2-induced oxidative damage and apoptosis in bovine mammary epithelial cells by promoting AMPK/NRF2 signaling, Journal of cellular physiology, 2020. 09. 03, doi: 10.1002/jcp.30035.

25. Ji Cheng#, Yufei Zhang#, Yusong Ge, Wen Li, Yu Cao, Yuhua Qu, Shengjun Liu, Yunlong Guo , Shoupeng Fu*, Juxiong Liu*,Sodiumbutyrate promotes milk fat synthesis in bovine mammary epithelial cells via GPR41 and its downstream signalling pathways, Life sciences, 2020. 10. 15, doi: 10.1016/j.lfs.2020.118375.

26. Wenjin Guo#, Juxiong Liu#, Shuang Hou, Guiqiu Hu, He Ma, Qian Gong, Xingchi Kan, Xin Ran, Yu Cao, Jianfa Wang, Shoupeng Fu*, The inflammatory environment mediated by a high-fat diet inhibited the development of mammary glands and destroyed the tight junction in pregnant mice, Food & Function, 2020. 09. 23, 11(9): 8193-8201.

27. Jiaxin Wang#, Yu Cao#, Shoupeng Fu#, Wen Li, Yusong Ge, Ji cheng, Juxiong Liu*, Niacin inhibits the synthesis of milk fat in BMECs through GPR109A-mediated downstream signaling pathway, Life sciences, 2020. 11. 01, doi: 10.1016/j.lfs.2020.118415.

28. Wenjin Guo#, Juxiong Liu#, Yuanxi Yang, He Ma, Qian Gong, Xingchi Kan, Xin Ran, Yu Cao, Jianfa Wang, ShoupengFu*, Guiqiu Hu. Rumen-bypassed tributyrin alleviates heat stress by reducing the inflammatory responses of immune cells, Poultry Science, 2021. 1, 100(1): 348-356.

29. Yu Cao#, Yan Zhang#, Lijun Ma, Jiaxin Wang, Wenjin Guo, Ji Cheng, Guiqiu Hu, Shoupeng Fu, Juxiong Liu*, Niacin stimulates EPH4EV mammary epithelial cell proliferation and mammary gland development in pubertal mice through activation of AKT/mTOR and ERK1/2 signaling pathways, Cell and tissue research, 2021. 5, 384(2): 313-324..

30. Yu Cao#, Guiqiu Hu#, Qing Zhang, Lijun Ma, Jiaxin Wang, Wen Li, Yusong Ge, Ji Cheng, Zhanqing Yang, Shoupeng Fu*, Juxiong Liu*, Kisspeptin-10 maintains the activation of the mTOR signaling pathway by inhibiting SIRT6 to promote the synthesis of milk in bovine mammary epithelial cells, Journal of agricultural and food chemistry, 2021. 4. 14, 69(14): 4093-4100.

31. Xingchi Kan#, Guiqiu Hu#, Bingxu Huang#, Wenjin Guo#, Yaping Huang, Yingsheng Chen, Ping Xu, Xiangyu Cai, Shoupeng Fu*, Juxiong Liu*, Pedunculoside protects against LPS-induced mastitis in mice by inhibiting inflammation and maintaining the integrity of blood-milk barrier, Aging-us, 2021. 8, 13(15):19460-19474.

32. Wenjin Guo#, Wen Li, Yingchun Su, Shu Liu, Xingchi Kan, Xin Ran, Yu Cao, Shoupeng Fu*, Juxiong Liu*, GPR109A alleviate mastitis and enhances blood milk barrier by activating AMPK/Nrf2 and autophagy, International journal of biological sciences, 2021.10.17, 17(15):4271-4284.

33. Xingchi Kan#, Juxiong Liu#, Xiangyu Cai, Yaping Huang, Ping Xu, Shoupeng Fu, Wenjin Guo, Guiqiu Hu*, Tartary buckwheat flavonoids relieve the tendency of mammary fibrosis induced by HFD during pregnancy and lactation, Aging-US, 2021.12.10, 13(28):25377-25392.

34. Xin Ran#, Juxiong Liu#, Shoupeng Fu#, Fuding He, Kefei Li, Guiqiu Hu*, Wenjin Guo*, Phytic acid maintains the integrity of blood-milk barrier by regulating inflammatory response and intestinal flora structure, Journal of agricultural and food chemistry, Journal of agricultural and food chemistry, 2022. 1. 12, 70(1):381-391.

35. Shiyao Xu#, Guiqiu Hu#, Di Wu, Xingchi Kan, Hisashi Oishi, Satoru Takahashi, Shoupeng Fu, Juxiong Liu*, Chuan Zhang*, MafK accelerates Salmonella mucosal infection through caspase-3 activation, Aging-us, 2022. 3. 8, 14(5):2287-2303.

36. Feng Li#, Guiqiu Hu#, Xiaoyu Long, Yu Cao, Qianqian Li, Wenjin Guo, Jiaxin Wang, Juxiong Liu*, Shoupeng Fu*, Stearic acid activates PI3K-mTOR-4EBP1/S6K and mTOR-SREBP-1 signal axis through FATP4-CDK1 to promote milk synthesis in bovine primary mammary epithelial cells, Journal of agricultural and food chemistry, 2022. 4. 6, 70(13):4007-4018.

1.主编《动物生理学》，2000年7月，吉林人民出版社。

2.主编《动物生理学前沿》，2003年8月，吉林人民出版社。

3.主编《动物生理学》，2011年7月，高等教育出版社。

1.吉林省自然科学学术成果奖，二等奖，吉林省自然科学学术成果评审委员会，2011年。

2.优秀学术成果奖，优秀奖，吉林省科学技术协会，2007年。

1.中国畜牧兽医学会动物生理生化学分会副理事长

2.吉林省生理学会理事长

3.吉林省神经科学学会副理事长