GU Jingmin

Title： Associate Professor

Specialties：Therapeutic phages of drug-resistant pathogens and their antibacterial related proteins.

Email：jingmin0629@163.com

Research Interests： 

· The phages of important antibacterial-resistant bacteria (such as S. aureus, E. faecium, E. faecalis, K. pneumoniae, E. coli, P. aeruginosa, etc.), Phage and antibacterial protein therapy.

· The mechanism of antibacterial protein (such as lysin, depolymerase, etc.) derived from phages.

· Interaction between bacteriophages and host bacteria.

Research Project:

1. National Natural Science Foundation of China, general project (32072824), 2021/01-2024/12.

2. National Natural Science Foundation of China, general project (31872505), 2019/01-2022/12.

3. National Natural Science Foundation of China, Youth Project (31502103), 2016/01-2018/12.

4. National Key R&D Program (2017YFD0501000), Sub-topics, 2017/017-2020/12.

5. Natural Science Foundation of Jilin Province, Outstanding Youth Project (20190103106JH, 2019/01-2020/12) and general project (20200201120JC, 2020/01-2022/12).

Selected Publications：

1. Wang X^#, …, Gu J^*. Therapeutic Efficacy of Phage PIZ SAE-01E2 Against Abortion Caused by Salmonella abortus equi in Mice. Appl Environ Microbiol. 2020 Sep 4:AEM.01366-20.

2. Ji Y^#,…., Gu J^*. Preventive effect of the phage VB-SavM-JYL01 on rabbit necrotizing pneumonia caused by Staphylococcus aureus. Vet Microbiol. 2019 Feb;229:72-80.

3. Zhang Y^#, ..,, Gu J^*. Antibacterial effects of phage lysin LysGH15 on planktonic cells and biofilms of diverse staphylococci. Appl Environ Microbiol. 2018 Jul 17;84(15).

4. Gu J, ..., Han W^*. Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin. PLoS Pathog. 2014 May 15;10(5):e1004109.

5. Gu J, …, Han W^*. LysGH15, a novel bacteriophage lysin, protects a murine bacteremia model efficiently against lethal methicillin-resistant Staphylococcus aureus infection. J Clin Microbiol. 2011 Jan;49(1):111-7.

Academic：

1. Excellent Doctoral Dissertation of Jilin Province.

2. Young member of the Veterinary Microbiology Professional Committee.

3. The first member of the Phage Group of the Medical Microbiology and Immunology Committee of the Chinese Society of Microbiology.

4. The Topic research editor of “Frontiers in Cellular and Infection Microbiology”.

5. The reviewer of Appl Environ Microbiol, Applied Microbiology and Biotechnology, Frontier in microbiology, Frontiers in Medicine, Antibiotics, Scientific Reports and Viruses, etc..