MO Xiaobing

MO Xiaobing obtained M.Sc. in Biochemistry and Molecular biology from Xiamen University in 2010. He then worked with Prof. Adam Yuan as a research assistant for two years. In 2013, he went to National University of Singapore and did his Ph.D. study in Biochemistry and structural biology. In 2017, as a postdoctoral fellow, he did research on Virology. In 2019, he went back to the College of Veterinary Medicine at Jilin University.

Research Interests：

1. Structural basis and functional implication for underlying immune

epitopes of key infectious viruses:

1) Virus isolation, purification and identification;

2) Cryo-EM: sample preparation, data collection and 3D structure reconstruction; Protein crystallization: diffraction using X-ray,

Structure determination.

2. Research and development of recombinant viral vaccine:

1) Vaccine quality control et al.

2) Gene cloning; protein expression; purification.

Selected Publications：

1. Bi, M., X. Li, W. Zhai, B. Yin, K. Tian andX. Mo*(2020). "Structural insight into the type-specific epitope of porcine circovirus type 3." Biosciences Rep 40(6). (Coresponding author)

2.Mo X*, Li X, Deng J, Yin B, Tian K* and Yuan YA (2019) Structural mechanism of virus-like-particle assembly of PCV2 capsid protein and identification of PCV2 type-specific epitope. PLOS Pathogens 15(3): e1007562. https://doi. org/10.1371/journal.ppat.1007562. (First author, *co-coresponding author)

3.Mo X, Yang X, Yuan YA* (2018) Structural insights intoDrosophila-C3PO complex assembly and 'Dynamic Side Port' model in substrate entry and release. Nucleic Acids Research. 46:8590-8604.

4. Xi X^#,Mo X^#, Y. Xiao, B. Yin, C. Lv, Y. Wang, Z. Sun, Q. Yang, Y. Yao, Y. Xuan, X. Li, Y. A. Yuan* and K. Tian*. (2016) Production ofEscherichia coli-based virus-like particle vaccine against porcine circovirus type 2 challenge in piglets: Structure characterization and protective efficacy validation. Journal of Biotechnology 223: 8-12. (^#Co-first author)

5. Zhang, T. Y^#., H. Y. Chen^#, J. L. Cao, H. L. Xiong,X. B. Mo, T. L. Li, X. Z. Kang, J. H. Zhao, B. Yin, X. Zhao, C. H. Huang, Q. Yuan*, D. Xue*, N. S. Xia* and Y. A. Yuan*. (2019) Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction. Nature Communications 10: 3192.

Awards：

The first prize in the 'Teaching Award' contest of College of Veterinary & The third prize in the 'Teaching Award' contest of Jilin University.