DU Xiliang
Title:Lecturer
Specialties:Animal Nutrition Metabolic Disease
Email:duxiliang@jlu.edu.cn; duxilianghaitao@163.com
Xiliang Du is a Lecturer of Jilin University. Dr. Du earned his Bachelor's degree from Shanxi Agriculture University in 2013, and received his Ph.D. from Jilin University in 2019. He is member of Chinese Society of Veterinary Internal Medicine. His recent interests include pathological mechanism of ketosis and fatty liver in dairy cows, the role of autophagy/mitophagy in the development of non-alcoholic fatty liver, and exploring of therapeutic targets and drugs for non-alcoholic fatty liver. In recent years, presided 3 projects form the National Natural Science Foundation and China Postdoctoral Science Foundation. Nine papers have been published in important international journals, such as J Dairy Sci, J Cell Physiol, Br J Pharmacol, etc.
Research Interests:
·The molecular mechanism of fatty liver and ketosis in dairy cows.
·Exploring of therapeutic targets and drugs for non-alcoholic fatty liver.
Selected Publications:
1. Li, X…Du, X.*, & Liu, G.* (2020). Cyanidin-3-O-glucoside improves non-alcoholic fatty liver disease by promoting PINK1-mediated mitophagy in mice. Br J Pharmacol, IF: 7.73, JCR Q1, Top.
2. Du, X…Li, X.*, & Liu, G.* (2018). High concentrations of fatty acids and β-hydroxybutyrate impair the growth hormone-mediated hepatic JAK2-STAT5 pathway in clinically ketotic cows. J Dairy Sci, IF: 3.33, JCR Q1, TOP. Cover Paper; Highly Cited Paper.
3. Du, X…Liu, G.*, & Li, X.* (2017). Acetoacetate induces hepatocytes apoptosis by the ROS-mediated MAPKs pathway in ketotic cows. J Cell Physiol, IF: 5.546, JCR Q1, Highly Cited Paper.
4. Du, X…Liu, G.*, & Li, X.* (2018). Adaptations of hepatic lipid metabolism and mitochondria in dairy cows with mild fatty liver. J Dairy Sci, IF: 3.33, JCR Q1, TOP.
5. Du, X.#, Liu, G.#, Loor, J. J.#... Li, X*. (2018). Impaired hepatic autophagic activity in dairy cows with severe fatty liver is associated with inflammation and reduced liver function. J Dairy Sci, IF: 3.33, JCR Q1, TOP.
Awards:
1. The first prize of Natural Academic Achievements of Jilin Province
2. Outstanding Graduates of Jilin University
3. Excellent Doctor Degree Dissertation of Jilin University